DIFFERENTIAL EFFECTS OF NEUROMUSCULAR BLOCKING AGENTS ON SUXAMETHONIUM-INDUCED FASCICULATIONS AND MYALGIA
نویسندگان
چکیده
منابع مشابه
Differential effects of neuromuscular blocking agents on suxamethonium-induced fasciculations and myalgia.
The effect of pretreatment with suxamethonium, gallamine or pancuronium on suxamethonium-induced fasciculations and myalgia was studied in a controlled, randomized and double-blind clinical trial. Both fasciculations and myalgia were assessed on a four-point rating scale. There was no significant correlation between fasciculations and postoperative muscle pain at 24, 48 or 72 h, and pretreatmen...
متن کاملSuxamethonium-induced myalgia.
Sir,—I read with interest the paper by Kahraman and colleagues on the effect of i.m. diclofenac on suxamethonium-induced myalgia [1]. Diclofenac, administered i.m. to conscious patients, is painful and has a tendency to cause sterile abscesses. Its use to ameliorate suxamethonium myalgia could be a case of a "remedy worse than the disease". Pretreatments have been tried previously but all have ...
متن کاملEffects of prostaglandins and indomethacin on neuromuscular blocking agents.
The effects on neuromuscular blockade by d-tubocurarine and succinylcholine of inhibition of prostaglandin biosynthesis by indomethacin and of intra-arterial administration of prostoglandins E2 and F2 alpha, before and after inhibition of prostoglandin biosynthesis, were evaluated in the cat sciatic-tibialis preparation. Non-specific inhibition of prostaglandin biosynthesis by indomethacin 3 mg...
متن کاملEFFECTS OF CHRONIC ADMINISTRATION OF TWO NEWLY SYNTHESIZED NONDEPOLARIZING NEUROMUSCULAR BLOCKING AGENTS
The potential changes In neuromuscular blockade after chronic (>24 h) administration of sub-paralytic doses of two newly introduced aminosteroidal muscle relaxants were investigated. Org-9426 (rocuronium) and Org-9487 were studied in the in vivo guinea pig gastrocnemius muscle-sciatic nerve preparation. The problems seen after prolonged administration of muscle relaxants are thought to ari...
متن کاملEffects of cholinesterase inhibitors on the neuromuscular blocking action of suxamethonium.
Prolonged neuromuscular block occurs when suxamethonium is given after neostigmine or pyridostigmine; however, studies of edrophonium and suxamethonium have yielded conflicting results. We have studied, therefore, interactions between suxamethonium and all three anticholinesterases in rats anaesthetized with pentobarbitone. After recovery from an initial bolus of suxamethonium, saline, edrophon...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1988
ISSN: 0007-0912
DOI: 10.1093/bja/60.4.367